Interference of Polydatin/Resveratrol in the ACE2:Spike Recognition during COVID-19 Infection. A Focus on Their Potential Mechanism of Action through Computational and Biochemical Assays

In the search for new therapeutic strategies to contrast SARS-CoV-2, we here studied the interaction of polydatin (PD) and resveratrol (RESV)—two natural stilbene polyphenols with manifold, well known biological activities—with Spike, the viral protein essential for virus entry into host cells, and...

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Veröffentlicht in:Biomolecules
Hauptverfasser: Perrella, Fulvio, Coppola, Federico, Petrone, Alessio, Platella, Chiara, Montesarchio, Daniela, Stringaro, Annarita, Ravagnan, Giampietro, Fuggetta, Maria Pia, Rega, Nadia, Musumeci, Domenica
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301781/
https://ncbi.nlm.nih.gov/pubmed/34356672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071048
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