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Stop Codon Context-Specific Induction of Translational Readthrough
Premature termination codon (PTC) mutations account for approximately 10% of pathogenic variants in monogenic diseases. Stimulation of translational readthrough, also known as stop codon suppression, using translational readthrough-inducing drugs (TRIDs) may serve as a possible therapeutic strategy...
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| Udgivet i: | Biomolecules |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8301745/ https://ncbi.nlm.nih.gov/pubmed/34356630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071006 |
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