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Stop Codon Context-Specific Induction of Translational Readthrough

Premature termination codon (PTC) mutations account for approximately 10% of pathogenic variants in monogenic diseases. Stimulation of translational readthrough, also known as stop codon suppression, using translational readthrough-inducing drugs (TRIDs) may serve as a possible therapeutic strategy...

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Bibliografske podrobnosti
izdano v:Biomolecules
Main Authors: Schilff, Mirco, Sargsyan, Yelena, Hofhuis, Julia, Thoms, Sven
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301745/
https://ncbi.nlm.nih.gov/pubmed/34356630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom11071006
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