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Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson’s disease

Apomorphine is an on‐demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine sublingual film (APL) and two formulations of s...

詳細記述

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書誌詳細
出版年:Clin Transl Sci
主要な著者: Agbo, Felix, Crass, Ryan L., Chiu, Yu‐Yuan, Chapel, Sunny, Galluppi, Gerald, Blum, David, Navia, Bradford
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301595/
https://ncbi.nlm.nih.gov/pubmed/33650272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.13008
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