Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson’s disease

Apomorphine is an on‐demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine sublingual film (APL) and two formulations of s...

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Bibliografische gegevens
Gepubliceerd in:Clin Transl Sci
Hoofdauteurs: Agbo, Felix, Crass, Ryan L., Chiu, Yu‐Yuan, Chapel, Sunny, Galluppi, Gerald, Blum, David, Navia, Bradford
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
Onderwerpen:
Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301595/
https://ncbi.nlm.nih.gov/pubmed/33650272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.13008
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