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Population pharmacokinetic analysis of apomorphine sublingual film or subcutaneous apomorphine in healthy subjects and patients with Parkinson’s disease

Apomorphine is an on‐demand treatment of “OFF” episodes in patients with Parkinson’s disease (PD). A joint parent‐metabolite population pharmacokinetic (PK) model characterized apomorphine and apomorphine‐sulfate following administration of apomorphine sublingual film (APL) and two formulations of s...

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Bibliografiska uppgifter
I publikationen:Clin Transl Sci
Huvudupphovsmän: Agbo, Felix, Crass, Ryan L., Chiu, Yu‐Yuan, Chapel, Sunny, Galluppi, Gerald, Blum, David, Navia, Bradford
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301595/
https://ncbi.nlm.nih.gov/pubmed/33650272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.13008
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