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Fine-Tuning the PI3K/Akt Signaling Pathway Intensity by Sex and Genotype-Load: Sex-Dependent Homozygotic Threshold for Somatic Growth but Feminization of Anxious Phenotype in Middle-Aged PDK1 K465E Knock-In and Heterozygous Mice

According to the Research Domain Criteria (RDoC), phenotypic differences among disorders may be explained by variations in the nature and degree of neural circuitry disruptions and/or dysfunctions modulated by several biological and environmental factors. We recently demonstrated the in vivo behavio...

詳細記述

保存先:
書誌詳細
出版年:Biomedicines
主要な著者: Santana-Santana, Mikel, Bayascas, José-Ramón, Giménez-Llort, Lydia
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301321/
https://ncbi.nlm.nih.gov/pubmed/34203450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9070747
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