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MCPIP1 Enhances TNF-α-Mediated Apoptosis through Downregulation of the NF-κB/cFLIP Axis

SIMPLE SUMMARY: TNF-α is considered to be a potential therapeutic drug for cancer, but the systemic toxicity problem still exists in clinical use. MCPIP1 plays a crucial role in anti-inflammatory and anti-viral contexts, as well as in the inhibition of cell growth. This study aims to investigate the...

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Bibliografiske detaljer
Udgivet i:Biology (Basel)
Main Authors: Suk, Fat-Moon, Chang, Chi-Ching, Sun, Pei-Chi, Ke, Wei-Ting, Chung, Chia-Chen, Lee, Kun-Lin, Chan, Tze-Sian, Liang, Yu-Chih
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8301320/
https://ncbi.nlm.nih.gov/pubmed/34356509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology10070655
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