Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NF-κB signalling

The anti-apoptotic cellular FLICE-like inhibitory protein cFLIP plays a pivotal role in normal tissues homoeostasis and the development of many tumors, but its role in normal thymus (NT), thymomas and thymic carcinomas (TC) is largely unknown. Expression, regulation and function of cFLIP were analyz...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Belharazem, Djeda, Grass, Albert, Paul, Cornelia, Vitacolonna, Mario, Schalke, Berthold, Rieker, Ralf J., Körner, Daniel, Jungebluth, Philipp, Simon-Keller, Katja, Hohenberger, Peter, Roessner, Eric M., Wiebe, Karsten, Gräter, Thomas, Kyriss, Thomas, Ott, German, Geserick, Peter, Leverkus, Martin, Ströbel, Philipp, Marx, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685693/
https://ncbi.nlm.nih.gov/pubmed/29163772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15929
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