Increased cFLIP expression in thymic epithelial tumors blocks autophagy via NF-κB signalling

The anti-apoptotic cellular FLICE-like inhibitory protein cFLIP plays a pivotal role in normal tissues homoeostasis and the development of many tumors, but its role in normal thymus (NT), thymomas and thymic carcinomas (TC) is largely unknown. Expression, regulation and function of cFLIP were analyz...

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Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Belharazem, Djeda, Grass, Albert, Paul, Cornelia, Vitacolonna, Mario, Schalke, Berthold, Rieker, Ralf J., Körner, Daniel, Jungebluth, Philipp, Simon-Keller, Katja, Hohenberger, Peter, Roessner, Eric M., Wiebe, Karsten, Gräter, Thomas, Kyriss, Thomas, Ott, German, Geserick, Peter, Leverkus, Martin, Ströbel, Philipp, Marx, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5685693/
https://ncbi.nlm.nih.gov/pubmed/29163772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15929
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