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Site-specific antibody fragment conjugates for targeted imaging

This work details the use of amber suppression-mediated genetic incorporation of unnatural amino acids (UAAs), specifically p-azido-l-phenylalanine (pAzF) and p-acetyl-l-phenylalanine (pAcF), to develop site-specifically labeled antibody Fab fragments. These antibody fragment conjugates represent a...

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Bibliografski detalji
Izdano u:Methods Enzymol
Glavni autori: Maloney, Robert, Buuh, Zakey Yusuf, Zhao, Yue, Wang, Rongsheng E.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8300489/
https://ncbi.nlm.nih.gov/pubmed/32416919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2020.02.023
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