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TGF-β regulates nerve growth factor expression in a mouse intervertebral disc injury model
BACKGROUND: Intervertebral disc (IVD) degeneration is a major cause of low back pain (LBP). Following disc injury, nerve growth factor (NGF) concentrations rise in IVDs, and anti-NGF therapy has been shown to attenuate LBP in humans. Increased levels of tumor necrosis factor-α (TNF-α) and transformi...
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| Publicado no: | BMC Musculoskelet Disord |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8299674/ https://ncbi.nlm.nih.gov/pubmed/34301215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-021-04509-w |
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