Elevated leptin levels induce inflammation through IL-6 in skeletal muscle of aged female rats

BACKGROUND: Chronic inflammation with aging contributes to sarcopenia. Previous studies have suggested that the accumulation of adipose tissue in skeletal muscle, referred to as intermuscular adipose tissue (IMAT), increases with age and is associated with inflammation. However, the mechanism govern...

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Bibliographic Details
Published in:BMC Musculoskelet Disord
Main Authors: Tazawa, Ryo, Uchida, Kentaro, Fujimaki, Hisako, Miyagi, Masayuki, Inoue, Gen, Sekiguchi, Hiroyuki, Murata, Kosuke, Takata, Ken, Kawakubo, Ayumu, Takaso, Masashi
Format: Artigo
Language:Inglês
Published: BioMed Central 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511122/
https://ncbi.nlm.nih.gov/pubmed/31077169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12891-019-2581-5
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