Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma: A Randomized Clinical Trial From the Children’s Oncology Group

IMPORTANCE: Brain tumors are the leading cause of disease-related death in children. Medulloblastoma is the most common malignant embryonal brain tumor, and strategies to increase survival are needed. OBJECTIVE: To evaluate therapy intensification with carboplatin as a radiosensitizer and isotretino...

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Publicat a:JAMA Oncol
Autors principals: Leary, Sarah E. S., Packer, Roger J., Li, Yimei, Billups, Catherine A., Smith, Kyle S., Jaju, Alok, Heier, Linda, Burger, Peter, Walsh, Karin, Han, Yuanyuan, Embry, Leanne, Hadley, Jennifer, Kumar, Rahul, Michalski, Jeff, Hwang, Eugene, Gajjar, Amar, Pollack, Ian F., Fouladi, Maryam, Northcott, Paul A., Olson, James M.
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2021
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299367/
https://ncbi.nlm.nih.gov/pubmed/34292305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2021.2224
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