MBCL-16. EFFICACY OF CARBOPLATIN GIVEN CONCOMITANTLY WITH RADIATION AND ISOTRETINOIN AS A PRO-APOPTOTIC AGENT IN MAINTENANCE THERAPY IN HIGH-RISK MEDULLOBLASTOMA: A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP

BACKGROUND: Metastasis, residual disease, and diffuse anaplasia are high-risk features in medulloblastoma. METHODS: This was a randomized phase 3 study. Patients age 3–21 years with high-risk medulloblastoma received (+/-) daily carboplatin with 36Gy craniospinal radiation and weekly Vincristine fol...

Full description

Saved in:
Bibliographic Details
Published in:Neuro Oncol
Main Authors: Leary, Sarah, Packer, Roger, Jaju, Alok, Heier, Linda, Burger, Peter, Smith, Kyle, Michalski, Jeff, Li, Yimei, Billups, Catherine, Hwang, Eugene, Gajjar, Amar, Pollack, Ian, Fouladi, Maryam, Northcott, Paul, Olson, James
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Medulloblastoma (Clinical)
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715378/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.492
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items