MBCL-16. EFFICACY OF CARBOPLATIN GIVEN CONCOMITANTLY WITH RADIATION AND ISOTRETINOIN AS A PRO-APOPTOTIC AGENT IN MAINTENANCE THERAPY IN HIGH-RISK MEDULLOBLASTOMA: A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP

BACKGROUND: Metastasis, residual disease, and diffuse anaplasia are high-risk features in medulloblastoma. METHODS: This was a randomized phase 3 study. Patients age 3–21 years with high-risk medulloblastoma received (+/-) daily carboplatin with 36Gy craniospinal radiation and weekly Vincristine fol...

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Dades bibliogràfiques
Publicat a:Neuro Oncol
Autors principals: Leary, Sarah, Packer, Roger, Jaju, Alok, Heier, Linda, Burger, Peter, Smith, Kyle, Michalski, Jeff, Li, Yimei, Billups, Catherine, Hwang, Eugene, Gajjar, Amar, Pollack, Ian, Fouladi, Maryam, Northcott, Paul, Olson, James
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Medulloblastoma (Clinical)
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7715378/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa222.492
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