Efficacy of Carboplatin and Isotretinoin in Children With High-risk Medulloblastoma: A Randomized Clinical Trial From the Children’s Oncology Group

IMPORTANCE: Brain tumors are the leading cause of disease-related death in children. Medulloblastoma is the most common malignant embryonal brain tumor, and strategies to increase survival are needed. OBJECTIVE: To evaluate therapy intensification with carboplatin as a radiosensitizer and isotretino...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Leary, Sarah E. S., Packer, Roger J., Li, Yimei, Billups, Catherine A., Smith, Kyle S., Jaju, Alok, Heier, Linda, Burger, Peter, Walsh, Karin, Han, Yuanyuan, Embry, Leanne, Hadley, Jennifer, Kumar, Rahul, Michalski, Jeff, Hwang, Eugene, Gajjar, Amar, Pollack, Ian F., Fouladi, Maryam, Northcott, Paul A., Olson, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2021
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8299367/
https://ncbi.nlm.nih.gov/pubmed/34292305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2021.2224
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