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Restoration of the ATG5-dependent autophagy sensitizes DU145 prostate cancer cells to chemotherapeutic drugs

Autophagy serves an important role in cancer cell survival and drug resistance. In the present study, the prostate cancer DU145 cell line was used, which lacks autophagy related 5 (ATG5) expression and is defective in induction of ATG5-dependent autophagy. The aim of the study was to examine the eff...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Peng, Ke, Sun, Aiqin, Zhu, Jun, Gao, Jinyi, Li, Yanlin, Shao, Genbao, Yang, Wannian, Lin, Qiong
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298997/
https://ncbi.nlm.nih.gov/pubmed/34386060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2021.12899
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