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Context-dependent effects of whole-genome duplication during mammary tumor recurrence
Whole-genome duplication (WGD) generates polyploid cells possessing more than two copies of the genome and is among the most common genetic abnormalities in cancer. The frequency of WGD increases in advanced and metastatic tumors, and WGD is associated with poor prognosis in diverse tumor types, sug...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8298634/ https://ncbi.nlm.nih.gov/pubmed/34294755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94332-z |
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