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Context-dependent effects of whole-genome duplication during mammary tumor recurrence

Whole-genome duplication (WGD) generates polyploid cells possessing more than two copies of the genome and is among the most common genetic abnormalities in cancer. The frequency of WGD increases in advanced and metastatic tumors, and WGD is associated with poor prognosis in diverse tumor types, sug...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Newcomb, Rachel, Dean, Emily, McKinney, Brock J., Alvarez, James V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298634/
https://ncbi.nlm.nih.gov/pubmed/34294755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94332-z
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