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14-3-3-protein regulates Nedd4-2 by modulating interactions between HECT and WW domains
Neural precursor cell expressed developmentally down-regulated 4 ligase (Nedd4-2) is an E3 ubiquitin ligase that targets proteins for ubiquitination and endocytosis, thereby regulating numerous ion channels, membrane receptors and tumor suppressors. Nedd4-2 activity is regulated by autoinhibition, c...
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| Publicado no: | Commun Biol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8298602/ https://ncbi.nlm.nih.gov/pubmed/34294877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02419-0 |
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