Structural Modulation of Phosducin by Phosphorylation and 14-3-3 Protein Binding

Phosducin (Pdc), a highly conserved phosphoprotein, plays an important role in the regulation of G protein signaling, transcriptional control, and modulation of blood pressure. Pdc is negatively regulated by phosphorylation followed by binding to the 14-3-3 protein, whose role is still unclear. To g...

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Hlavní autoři: Rezabkova, Lenka, Kacirova, Miroslava, Sulc, Miroslav, Herman, Petr, Vecer, Jaroslav, Stepanek, Miroslav, Obsilova, Veronika, Obsil, Tomas
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2012
Témata:
Proteins and Nucleic Acids
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3491691/
https://ncbi.nlm.nih.gov/pubmed/23199924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.09.021
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