Structural Basis for the 14-3-3 Protein-dependent Inhibition of the Regulator of G Protein Signaling 3 (RGS3) Function

Regulator of G protein signaling (RGS) proteins function as GTPase-activating proteins for the α-subunit of heterotrimeric G proteins. The function of certain RGS proteins is negatively regulated by 14-3-3 proteins, a family of highly conserved regulatory molecules expressed in all eukaryotes. In th...

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Hlavní autoři: Rezabkova, Lenka, Man, Petr, Novak, Petr, Herman, Petr, Vecer, Jaroslav, Obsilova, Veronika, Obsil, Tomas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3234818/
https://ncbi.nlm.nih.gov/pubmed/22027839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.273573
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