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14-3-3 Protein Masks the DNA Binding Interface of Forkhead Transcription Factor FOXO4
The role of 14-3-3 proteins in the regulation of FOXO forkhead transcription factors is at least 2-fold. First, the 14-3-3 binding inhibits the interaction between the FOXO and the target DNA. Second, the 14-3-3 proteins prevent nuclear reimport of FOXO factors by masking their nuclear localization...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2740560/ https://ncbi.nlm.nih.gov/pubmed/19416966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.002725 |
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