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BCG therapy is associated with long-term, durable induction of Treg signature genes by epigenetic modulation

Induction of immunosuppressive T-regulatory cells (Tregs) is a desirable goal in autoimmunity, and perhaps other immune diseases of activation. One promising avenue is with the bacille-calmette-guérin (BCG) vaccine in autoimmune type 1 diabetes (T1D). Its administration is associated with gradual cl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Keefe, Ryan C., Takahashi, Hiroyuki, Tran, Lisa, Nelson, Kacie, Ng, Nathan, Kühtreiber, Willem M., Faustman, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298580/
https://ncbi.nlm.nih.gov/pubmed/34294806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94529-2
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