BCG Vaccinations Upregulate Myc, a Central Switch for Improved Glucose Metabolism in Diabetes

Myc has emerged as a pivotal transcription factor for four metabolic pathways: aerobic glycolysis, glutaminolysis, polyamine synthesis, and HIF-1α/mTOR. Each of these pathways accelerates the utilization of sugar. The BCG vaccine, a derivative of Mycobacteria-bovis, has been shown to trigger a long-...

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Publicado no:iScience
Main Authors: Kühtreiber, Willem M., Takahashi, Hiroyuki, Keefe, Ryan C., Song, Yaerin, Tran, Lisa, Luck, Trevor G., Shpilsky, Gabriella, Moore, Louisa, Sinton, Sarah M., Graham, Jessica C., Faustman, Denise L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205768/
https://ncbi.nlm.nih.gov/pubmed/32380424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101085
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