Heterotopic ossification in mice overexpressing Bmp2 in Tie2+ lineages

Bone morphogenetic protein (Bmp) signaling is critical for organismal development and homeostasis. To elucidate Bmp2 function in the vascular/hematopoietic lineages we generated a new transgenic mouse line in which ectopic Bmp2 expression is controlled by the Tie2 promoter. Tie2(CRE/+);Bmp2(tg/tg) m...

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Publicat a:Cell Death Dis
Autors principals: Prados, Belén, del Toro, Raquel, MacGrogan, Donal, Gómez-Apiñániz, Paula, Papoutsi, Tania, Muñoz-Cánoves, Pura, Méndez-Ferrer, Simón, de la Pompa, José Luis
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8298441/
https://ncbi.nlm.nih.gov/pubmed/34294700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-04003-0
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