Substance P Signaling Mediates BMP Dependent Heterotopic Ossification

Heterotopic ossification (HO) is a disabling condition associated with neurologic injury, inflammation, and overactive BMP signaling. The inductive factors involved in lesion formation are unknown. We found that the expression of the neuro-inflammatory factor Substance P (SP) is dramatically increas...

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Hauptverfasser: Kan, Lixin, Lounev, Vitali Y, Pignolo, Robert J, Duan, Lishu, Liu, Yijie, Stock, Stuart R, McGuire, Tammy L, Lu, Bao, Gerard, Norma P, Shore, Eileen M, Kaplan, Frederick S, Kessler, John A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508732/
https://ncbi.nlm.nih.gov/pubmed/21748788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.23259
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