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Cellular Hypoxia Promotes Heterotopic Ossification by Amplifying BMP Signaling
Hypoxia and inflammation are implicated in the episodic induction of heterotopic endochondral ossification (HEO); however, the molecular mechanisms are unknown. HIF-1α integrates the cellular response to both hypoxia and inflammation and is a prime candidate for regulating HEO. We investigated the r...
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| Izdano u: | J Bone Miner Res |
|---|---|
| Glavni autori: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5010462/ https://ncbi.nlm.nih.gov/pubmed/27027798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.2848 |
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