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Enhancing myelin renewal reverses cognitive dysfunction in a murine model of Alzheimer’s disease
Severe cognitive decline is a hallmark of Alzheimer’s disease (AD). In addition to grey matter loss, significant white matter pathology has been identified in AD patients. Here, we characterized the dynamics of myelin generation and loss in the APP/PS1 mouse model of AD. Unexpectedly, we observed a...
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| Publicat a: | Neuron |
|---|---|
| Autors principals: | , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8298291/ https://ncbi.nlm.nih.gov/pubmed/34102111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2021.05.012 |
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