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Proteasomal adaptations to FDA-approved proteasome inhibitors: a potential mechanism for drug resistance?

With proteasome inhibitors (PIs) becoming clinically available since 2003, outcomes for patients with multiple myeloma (MM) have dramatically changed, improving quality of life and survival. Despite the impressive treatment success, however, almost all MM patients who initially respond to these PIs...

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Bibliografiske detaljer
Udgivet i:Cancer Drug Resist
Hovedforfatter: Kim, Kyung Bo
Format: Artigo
Sprog:Inglês
Udgivet: OAE Publishing Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297691/
https://ncbi.nlm.nih.gov/pubmed/34308274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20517/cdr.2021.27
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