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Transcriptomic Profiling of Control and Thyroid-Associated Orbitopathy (TAO) Orbital Fat and TAO Orbital Fibroblasts Undergoing Adipogenesis

PURPOSE: Orbital fat hyperplasia commonly occurs in thyroid-associated orbitopathy (TAO). To understand molecular mechanisms underlying orbital adipogenesis, we used transcriptomics to compare gene expression in controls and patients with TAO, as well as in orbital fibroblasts (OFs) undergoing adipo...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Kim, Dong Won, Taneja, Kamil, Hoang, Thanh, Santiago, Clayton P., McCulley, Timothy J., Merbs, Shannath L., Mahoney, Nicholas R., Blackshaw, Seth, Rajaii, Fatemeh
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2021
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297424/
https://ncbi.nlm.nih.gov/pubmed/34269815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.9.24
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