Transcriptomic Profiling of Control and Thyroid-Associated Orbitopathy (TAO) Orbital Fat and TAO Orbital Fibroblasts Undergoing Adipogenesis

PURPOSE: Orbital fat hyperplasia commonly occurs in thyroid-associated orbitopathy (TAO). To understand molecular mechanisms underlying orbital adipogenesis, we used transcriptomics to compare gene expression in controls and patients with TAO, as well as in orbital fibroblasts (OFs) undergoing adipo...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Kim, Dong Won, Taneja, Kamil, Hoang, Thanh, Santiago, Clayton P., McCulley, Timothy J., Merbs, Shannath L., Mahoney, Nicholas R., Blackshaw, Seth, Rajaii, Fatemeh
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2021
Assuntos:
Anatomy and Pathology/Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297424/
https://ncbi.nlm.nih.gov/pubmed/34269815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.9.24
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