Transcriptomic Profiling of Control and Thyroid-Associated Orbitopathy (TAO) Orbital Fat and TAO Orbital Fibroblasts Undergoing Adipogenesis

PURPOSE: Orbital fat hyperplasia commonly occurs in thyroid-associated orbitopathy (TAO). To understand molecular mechanisms underlying orbital adipogenesis, we used transcriptomics to compare gene expression in controls and patients with TAO, as well as in orbital fibroblasts (OFs) undergoing adipo...

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Pubblicato in:Invest Ophthalmol Vis Sci
Autori principali: Kim, Dong Won, Taneja, Kamil, Hoang, Thanh, Santiago, Clayton P., McCulley, Timothy J., Merbs, Shannath L., Mahoney, Nicholas R., Blackshaw, Seth, Rajaii, Fatemeh
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Association for Research in Vision and Ophthalmology 2021
Soggetti:
Anatomy and Pathology/Oncology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8297424/
https://ncbi.nlm.nih.gov/pubmed/34269815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.9.24
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