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MDM2/X Inhibitors as Radiosensitizers for Glioblastoma Targeted Therapy

Inhibition of the MDM2/X-p53 interaction is recognized as a potential anti-cancer strategy, including the treatment of glioblastoma (GB). In response to cellular stressors, such as DNA damage, the tumor suppression protein p53 is activated and responds by mediating cellular damage through DNA repair...

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Detaylı Bibliyografya
Yayımlandı:Front Oncol
Asıl Yazarlar: Miles, Xanthene, Vandevoorde, Charlot, Hunter, Alistair, Bolcaen, Julie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2021
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296304/
https://ncbi.nlm.nih.gov/pubmed/34307171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.703442
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