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MDM2/X Inhibitors as Radiosensitizers for Glioblastoma Targeted Therapy

Inhibition of the MDM2/X-p53 interaction is recognized as a potential anti-cancer strategy, including the treatment of glioblastoma (GB). In response to cellular stressors, such as DNA damage, the tumor suppression protein p53 is activated and responds by mediating cellular damage through DNA repair...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Miles, Xanthene, Vandevoorde, Charlot, Hunter, Alistair, Bolcaen, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8296304/
https://ncbi.nlm.nih.gov/pubmed/34307171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.703442
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