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Rapid in vitro quantification of TDP-43 and FUS mislocalisation for screening of gene variants implicated in frontotemporal dementia and amyotrophic lateral sclerosis

Identified genetic mutations cause 20% of frontotemporal dementia (FTD) and 5-10% of amyotrophic lateral sclerosis (ALS) cases: however, for the remainder of patients the origin of disease is uncertain. The overlap in genetic, clinical and pathological presentation of FTD and ALS suggests these two...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Oyston, Lisa J., Ubiparipovic, Stephanie, Fitzpatrick, Lauren, Hallupp, Marianne, Boccanfuso, Lauren M., Kwok, John B., Dobson-Stone, Carol
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group UK 2021
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295343/
https://ncbi.nlm.nih.gov/pubmed/34290285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94225-1
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