Spectral fitting strategy to overcome the overlap between 2-hydroxyglutarate and lipid resonances at 2.25 ppm

PURPOSE: (1)H MRS provides a noninvasive tool for identifying mutations in isocitrate dehydrogenase (IDH). Quantification of the prominent 2-hydroxyglutarate (2HG) resonance at 2.25 ppm is often confounded by the lipid resonance at the same frequency in tumors with elevated lipids. We propose a new...

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Publicado no:Magn Reson Med
Main Authors: Askari, Pegah, Dimitrov, Ivan E., Ganji, Sandeep K., Tiwari, Vivek, Levy, Michael, Patel, Toral R., Pan, Edward, Mickey, Bruce E., Malloy, Craig R., Maher, Elizabeth A., Choi, Changho
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295210/
https://ncbi.nlm.nih.gov/pubmed/33977579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.28829
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