Early, empiric high-dose leucovorin rescue in lymphoma patients treated with sequential doses of high-dose methotrexate

BACKGROUND: In patients exposed to high-dose methotrexate (HDMTX; ≥1g/m(2)) with a history of elevated methotrexate (MTX) concentrations during previous doses, it is unclear whether prescribing high-dose leucovorin (HDLV) rescue limits future high levels or reduces the likelihood of acute kidney inj...

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Publicat a:Support Care Cancer
Autors principals: Barreto, Jason N., Peterson, Kristen T., Barreto, Erin F., Mara, Kristin C., Dierkhising, Ross A., Leung, Nelson, Witzig, Thomas E., Thompson, Carrie A.
Format: Artigo
Idioma:Inglês
Publicat: 2021
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8295178/
https://ncbi.nlm.nih.gov/pubmed/33661366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00520-021-06106-y
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