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Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst attenuation of the cyclic AMP response element-binding protein

The cAMP response element-binding protein (CREB) is an important regulator of cell growth, metabolism, and synaptic plasticity. CREB is activated through phosphorylation of an evolutionarily conserved Ser residue (S133) within its intrinsically disordered kinase-inducible domain (KID). Phosphorylati...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Kim, Sang Hwa, Wu, Cheng-Guo, Jia, Weiyan, Xing, Yongna, Tibbetts, Randal S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294589/
https://ncbi.nlm.nih.gov/pubmed/34171357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100908
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