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Roles of constitutive and signal-dependent protein phosphatase 2A docking motifs in burst attenuation of the cyclic AMP response element-binding protein

The cAMP response element-binding protein (CREB) is an important regulator of cell growth, metabolism, and synaptic plasticity. CREB is activated through phosphorylation of an evolutionarily conserved Ser residue (S133) within its intrinsically disordered kinase-inducible domain (KID). Phosphorylati...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kim, Sang Hwa, Wu, Cheng-Guo, Jia, Weiyan, Xing, Yongna, Tibbetts, Randal S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294589/
https://ncbi.nlm.nih.gov/pubmed/34171357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100908
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