PB1-F2 amyloid-like fibers correlate with proinflammatory signaling and respiratory distress in influenza-infected mice

PB1-F2 is a virulence factor of influenza A virus known to increase viral pathogenicity in mammalian hosts. PB1-F2 is an intrinsically disordered protein displaying a propensity to form amyloid-like fibers. However, the correlation between PB1-F2 structures and the resulting inflammatory response is...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chevalier, Christophe, Leymarie, Olivier, Sedano, Laura, Da Costa, Bruno, Richard, Charles-Adrien, Maisonnasse, Pauline, Réfregiers, Matthieu, Jamme, Frédéric, Le Goffic, Ronan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8294585/
https://ncbi.nlm.nih.gov/pubmed/34146545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100885
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