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The Influenza Virus Protein PB1-F2 Increases Viral Pathogenesis through Neutrophil Recruitment and NK Cells Inhibition

The influenza A virus (IAV) PB1-F2 protein is a virulence factor contributing to the pathogenesis observed during IAV infections in mammals. In this study, using a mouse model, we compared the host response associated with PB1-F2 with an early transcriptomic signature that was previously associated...

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Publicat a:PLoS One
Autors principals: Vidy, Aurore, Maisonnasse, Pauline, Da Costa, Bruno, Delmas, Bernard, Chevalier, Christophe, Le Goffic, Ronan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087861/
https://ncbi.nlm.nih.gov/pubmed/27798704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165361
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