PB1-F2 Influenza A Virus Protein Adopts a β-Sheet Conformation and Forms Amyloid Fibers in Membrane Environments

The influenza A virus PB1-F2 protein, encoded by an alternative reading frame in the PB1 polymerase gene, displays a high sequence polymorphism and is reported to contribute to viral pathogenesis in a sequence-specific manner. To gain insights into the functions of PB1-F2, the molecular structure of...

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Detalhes bibliográficos
Main Authors: Chevalier, Christophe, Al Bazzal, Ali, Vidic, Jasmina, Février, Vincent, Bourdieu, Christiane, Bouguyon, Edwige, Le Goffic, Ronan, Vautherot, Jean-François, Bernard, Julie, Moudjou, Mohammed, Noinville, Sylvie, Chich, Jean-François, Da Costa, Bruno, Rezaei, Human, Delmas, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857135/
https://ncbi.nlm.nih.gov/pubmed/20172856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.067710
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