Targeting UHRF1-dependent DNA repair selectively sensitizes KRAS mutant lung cancer to chemotherapy

Kirsten rat sarcoma virus oncogene homolog (KRAS) mutant lung cancer remains a challenge to cure and chemotherapy is the current standard treatment in the clinic. Hence, understanding molecular mechanisms underlying the sensitivity of KRAS mutant lung cancer to chemotherapy could help uncover unique...

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Udgivet i:Cancer Lett
Main Authors: Tian, Danmei, Tang, Jinshan, Geng, Xinran, Li, Qingwen, Wang, Fangfang, Zhao, Huadong, Narla, Goutham, Yao, Xinsheng, Zhang, Youwei
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293908/
https://ncbi.nlm.nih.gov/pubmed/32814087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.08.008
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