Targeting UHRF1-dependent DNA repair selectively sensitizes KRAS mutant lung cancer to chemotherapy

Kirsten rat sarcoma virus oncogene homolog (KRAS) mutant lung cancer remains a challenge to cure and chemotherapy is the current standard treatment in the clinic. Hence, understanding molecular mechanisms underlying the sensitivity of KRAS mutant lung cancer to chemotherapy could help uncover unique...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Tian, Danmei, Tang, Jinshan, Geng, Xinran, Li, Qingwen, Wang, Fangfang, Zhao, Huadong, Narla, Goutham, Yao, Xinsheng, Zhang, Youwei
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293908/
https://ncbi.nlm.nih.gov/pubmed/32814087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2020.08.008
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