Renal Inflammation and Innate Immune Activation Underlie the Transition From Gentamicin-Induced Acute Kidney Injury to Renal Fibrosis

Subjects recovering from acute kidney injury (AKI) are at risk of developing chronic kidney disease (CKD). The mechanisms underlying this transition are unclear and may involve sustained activation of renal innate immunity, with resulting renal inflammation and fibrosis. We investigated whether the...

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Опубликовано в: :Front Physiol
Главные авторы: Albino, Amanda Helen, Zambom, Fernanda Florencia Fregnan, Foresto-Neto, Orestes, Oliveira, Karin Carneiro, Ávila, Victor Ferreira, Arias, Simone Costa Alarcon, Seguro, Antonio Carlos, Malheiros, Denise Maria Avancini Costa, Camara, Niels Olsen Saraiva, Fujihara, Clarice Kazue, Zatz, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
Предметы:
Physiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8293269/
https://ncbi.nlm.nih.gov/pubmed/34305624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2021.606392
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