Glucagon-Like Peptide-1 Receptor Agonist Ameliorates 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP) Neurotoxicity Through Enhancing Mitophagy Flux and Reducing α-Synuclein and Oxidative Stress

Parkinson disease (PD) is the second most common neurodegenerative disease without known disease modification therapy to slow down disease progression. This disease has pathological features of Lewy bodies with α-synuclein aggregation being the major component and selective dopaminergic neuronal los...

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Dades bibliogràfiques
Publicat a:Front Mol Neurosci
Autors principals: Lin, Tsu-Kung, Lin, Kai-Jung, Lin, Hung-Yu, Lin, Kai-Lieh, Lan, Min-Yu, Wang, Pei-Wen, Wang, Tzu-Jou, Wang, Feng-Sheng, Tsai, Po-Chin, Liou, Chia-Wei, Chuang, Jiin-Haur
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Molecular Neuroscience
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292641/
https://ncbi.nlm.nih.gov/pubmed/34305527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.697440
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