Dopamine receptor 3 might be an essential molecule in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity

BACKGROUND: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces Parkinson’s disease (PD)-like neurodegeneration of dopaminergic neurons in the substantia nigra pars compacta (SNpc) via its oxidized product, 1-methyl-4-phenylpyridinium (MPP+), which is transported by the dopamine (DA) transpo...

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Detalhes bibliográficos
Main Authors: Chen, Yan, Ni, Ying-yin, Liu, Jie, Lu, Jia-wei, Wang, Fang, Wu, Xiao-lin, Gu, Ming-min, Lu, Zhen-yu, Wang, Zhu-gang, Ren, Zhi-hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734004/
https://ncbi.nlm.nih.gov/pubmed/23902361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-14-76
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