High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma

Conventional chemotherapeutic agents are nonselective, often resulting in severe side effects and the development of resistance. Therefore, new molecular-targeted therapies are urgently needed to be integrated into existing treatment regimens. Here, we performed a high-throughput compound screen to...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tuomainen, Katja, Hyytiäinen, Aini, Al-Samadi, Ahmed, Ianevski, Philipp, Ianevski, Aleksandr, Potdar, Swapnil, Turunen, Laura, Saarela, Jani, Kuznetsov, Sergey, Wahbi, Wafa, Risteli, Maija, Mäkitie, Antti, Monni, Outi, Salo, Tuula
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8292418/
https://ncbi.nlm.nih.gov/pubmed/34285300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-94259-5
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